Reduction of Intraepidermal Nerve Fiber Density (IENFD) in the skin biopsies of patients with fibromyalgia: A controlled study - Journal of the Neurological Sciences
"Conclusion: This is one of the largest series of FM patients
demonstrating a significant reduction of IENFD in their skin biopsies.
The findings indicate that in a subset of FM patients, the pain
syndrome is, at least partially, of neuropathic origin. Skin biopsy
may prove a useful tool and a potential biomarker in future studies of