Tuesday, July 15, 2008

Relationship Between Fibromyalgia and Major Depressive Disorder: a Comprehensive Review

DFW_CFIDS - The Relationship Between Fibromyalgia and Major Depressive Disorder: a Comprehensive Review: "The Relationship Between Fibromyalgia and Major Depressive Disorder"

A large body of evidence suggests that the relationship between major depressive disorder (MDD) and fibromyalgia (FM) is complex. Improved understanding of this relationship promises to provide clinicians with better assessment and treatment options for both disorders. . .

This paper reviews research on the prevalence, etiology and pathogenesis, clinical characterization, and treatment of FM and MDD, as well as studies that examined the relationship between these disorders. Studies were identified via PubMed literature search.

Our findings point to substantial similarities in neuroendocrine abnormalities, psychological characteristics, physical symptoms and treatments between FM and MDD. However, currently available findings do not support the assumption that MDD and FM refer to the same underlying construct or can be seen as subsidiaries of one disease concept.

New methodological and theoretical approaches may lead to a better understanding of the link between FM and MDD, and to more effective psychological and psychopharmacological therapies for FM patients. In the meantime, clinicians should carefully screen for a history of MDD in patients with FM.

Source: The relationship between fibromyalgia and major depressive disorder: a comprehensive review. Curr Med Res Opin. 2008 Jul 4;

Authors: Pae CU, Luyten P, Marks DM, Han C, Park SH, Patkar AA, Masand PS, Van Houdenhove"

So a complex relationship indeed, I certainly agree with that having spent months in a psychiatric hospital, almost a zombie until ECT seemed to bring me back to life just a little bit.

I have never fully recovered and struggle to fight off further reactive depression caused by pain and isolation. A When every day is a struggle it makes my life very little....and very hard to look forward to anything

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