What causes RBCs to become sticky in the first place

What causes RBCs to become sticky in the first place

Expert:  Carlos replied 3 years ago.

Dear JACUSTOMER 9avzrh26:Agglutination (clumping) of type A red blood cells (RBCs) by anti-A antibodies. The antibodies have two combining sites and are able to attach to the A antigens on adjacent RBCs, thus causing the RBCs to bond together.

Stickiness of red blood cells or the clumping of the red blood cells together is called autoagglutination.
The presence of antibodies (usually IgM) on the surface of red blood cells is responsible for the phenomenon of autoagglutination. Agglutination can be observed during immune-mediated hemolytic anemia, but also during 'cryoglobulinemia' ( a far more rare condition).

Read more: http://www.justanswer.com/health/53x6z-causes-rbcs-become-sticky-first-place.html#ixzz3S7paoxo7

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